Abstract #0268

Motion-Corrected 350 &[mu]m Isotropic MPRAGE at 3 T Using Volumetric Navigators (VNavs)

Matthew Dylan Tisdall¹,², Jonathan R. Polimeni¹,², Andr J. W. van der Kouwe¹,²

¹A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; ²Radiology, Harvard Medical School, Boston, MA, United States

350 um isotropic imaging at 3 T requires very long scan times, and subject motion is a critical impediment. We demonstrate the use of volumetric navigators (vNavs) for prospective motion and frequency correction, and the use of inner-loop GRAPPA in a MPRAGE to maintain desirable contrast as seen at 1mm. Combined, these techniques allow successful 350 um isotropic imaging of a healthy volunteer without additional restraint.