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Abstract #0357

Magnetic Resonance Imaging Detects Therapeutic Effects of Endothelial Progenitor Cells on Tissue Repair and Muscle Regeneration Into Ischemia Hindlimb

Xingui Peng1, Shenghong Ju1, Judy Rose James2, Darya P. Shlapak2

1Jiangsu Key Laboratory of Molecular and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, Jiangsu Province, China; 2Department of Radiology, University of Mississippi Medical Center, Jackson, MS, United States

This study aimed to use the diffusion tensor imaging (DTI) and T2 weighted MR imaging to assess the therapeutic effect of endothelia progenitor cell in a mouse model of hind limb ischemia. DTI can be used as a marker in vivo and as a diagnostic tool for assessment of ischemia-induced muscle damage and repair.