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Abstract #0451

A Fingerprinting Approach to Compute Blood Volume, Vessel Diameter and Blood Oxygenation Maps in the Human Brain

Thomas Christen1, Nicolas Pannetier2, 3, Wendy W. Ni1, Deqiang Qiu1, Norbert Schuff2, 3, Michael E. Moseley1, Greg Zaharchuk1

1Radiology, Stanford University, Stanford, CA, United States; 2Radiology, University of California San Francisco, San Francisco, CA, United States; 3Center for Imaging of Neurodegenerative diseases, Veterans Affairs Medical Centre, San Francisco, CA, United States

In this work, we acquired the MR signal time evolution (FID and spin echo) pre and post injection of an intravascular contrast agent in volunteers. We then compared the ratio of the signals to a dictionary of curves obtained using advanced numerical simulations. We show that it is possible with this approach to extract quantitative information about the microvascular network.