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Abstract #0450

Anatomical and ASL Imaging of the Retina at 7 T

Daniel James Lee1, Ehsan Vaghefi2, Kevin F. Webb, Alexander J E Foss3, Richard W. Bowtell1, Susan T. Francis1

1SPMMRC, University of Nottingham, Nottingham, Nottinghamshire, United Kingdom; 2University of Auckland, Auckland, New Zealand; 3Queen's Medical Centre, Nottingham, Nottinghamshire, United Kingdom

Using a dedicated receive coil and the high signal-to-noise of a 7 T system, high resolution anatomical images of the human eye have been obtained in vivo. Perfusion images showing retinal blood flow were acquired using a FAIR ASL scheme with a TurboFLASH readout across a range of post-label delay times (TI) , showing largest perfusion signals at the longest TI used here (1550 ms), with average baseline perfusion of 104 41 ml/100 mL/min . Perfusion changes in response to 8 Hz visual stimulation were measured and a 61 % increase in retinal perfusion is detected.