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Abstract #0460

Non-Invasive Investigation of the Compartmentalization of Iron in the Human Brain

Ferdinand Schweser1, 2, Jan Sedlacik3, Andreas Deistung1, Jrgen R. Reichenbach1

1Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany; 2School of Medicine, Friedrich Schiller University Jena, Jena, Germany; 3Neuroradiolology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Abnormal accumulation of iron in the brain is known to be associated with several neurodegenerative diseases such as multiple sclerosis or Parkinsons disease. In this contribution we show how a combination of R2* mapping and QSM can be used to infer on the compartmentalization of brain iron in vivo.