Abstract #0460

Non-Invasive Investigation of the Compartmentalization of Iron in the Human Brain

Ferdinand Schweser¹,², Jan Sedlacik³, Andreas Deistung¹, Jrgen R. Reichenbach¹

¹Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany; ²School of Medicine, Friedrich Schiller University Jena, Jena, Germany; ³Neuroradiolology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Abnormal accumulation of iron in the brain is known to be associated with several neurodegenerative diseases such as multiple sclerosis or Parkinsons disease. In this contribution we show how a combination of R₂^* mapping and QSM can be used to infer on the compartmentalization of brain iron in vivo.