1Department
of Physics and Astronomy, Vanderbilt University, Nashville, TN, United
States; 2Vanderbilt University Institute of Imaging Science,
Nashville, TN, United States; 3Department of Radiology, Vanderbilt
University, Nashville, TN, United States
A novel technique is explained for producing chemical exchange rate dependent images and describes how to analyze these images to calculate exchange rates for model systems. Samples containing Glucose and Creatine were imaged and analyzed to calculate exchange rates of 5,750 Hz and 499 Hz respectively, which are reasonably close to previously reported values in the literature. This technique can theoretically be extended to calculate exchange rates of separate pools in mixtures as well, which will be of great interest moving forward.
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