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Abstract #0641

In Vivo Comparison of Intravenous and Intra-Articular DGEMRIC and Delayed Quantitative CT Arthrography

Jukka Hirvasniemi1, Katariina A.M. Kulmala2, Eveliina Lammentausta3, Risto Ojala4, Petri Lehenkari5, 6, Alaaeldin Kamel3, Jukka S. Jurvelin2, Juha Tyrs2, 7, Miika T. Nieminen3, 4, Simo Saarakkala1, 3

1Department of Medical Technology, University of Oulu, Oulu, Finland; 2Department of Applied Physics, University of Eastern Finland, Kuopio, Finland; 3Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland; 4Department of Diagnostic Radiology, University of Oulu, Oulu, Finland; 5Department of Anatomy and Cell Biology, University of Oulu, Oulu, Finland; 6Department of Surgery, Oulu University Hospital, Oulu, Finland; 7Department of Clinical Neurophysiology, Kuopio University Hospital, Kuopio, Finland

dGEMRIC with intravenous (dGEMRICIV) and intra-articular contrast agent injection (dGEMRICIA) and delayed quantitative CT arthrography (dQCTA) were compared in a patient study. dGEMRICIV and dGEMRICIA were performed at 90 minutes after gadopentetate injection. dQCTA was performed at 5 and 45 minutes after intra-articular injection of ioxaglate. Normalized dQCTA was in best agreement with dGEMRICIV at 45 minutes after ioxaglate injection (rs=0.72). dGEMRICIV and dGEMRICIA were not correlated without taking account of synovial fluid. The findings of the study indicate the importance of taking account of the contrast agent concentration in synovial fluid in dQCTA and dGEMRICIA.