Abstract #0642

Molecular MR Imaging of Pulmonary Fibrosis in a Mouse Model

Peter Caravan¹, Yan Yang¹, Roshini Zachariah², David E. Sosnovik¹, Guangping Dai¹, Bryan Fuchs², Michael Lanuti²

¹A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; ²Surgery, Massachusetts General Hospital, Boston, MA, United States

Pulmonary fibrosis is a devastating disease with poor clinical outcomes. We show that ultrashort TE imaging with a collagen-targeted gadolinium-based MR probe can specifically identify pulmonary fibrosis in a mouse model of disease.