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Abstract #0642

Molecular MR Imaging of Pulmonary Fibrosis in a Mouse Model

Peter Caravan1, Yan Yang1, Roshini Zachariah2, David E. Sosnovik1, Guangping Dai1, Bryan Fuchs2, Michael Lanuti2

1A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States; 2Surgery, Massachusetts General Hospital, Boston, MA, United States

Pulmonary fibrosis is a devastating disease with poor clinical outcomes. We show that ultrashort TE imaging with a collagen-targeted gadolinium-based MR probe can specifically identify pulmonary fibrosis in a mouse model of disease.