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Abstract #0643

High-Resolution UTE MRI Longitudinal Non-Invasive Characterization of a Mouse Model of Chronic Asthma: From Inflammation to Bronchial Remodeling Assessment

Andrea Bianchi1, Annaig Ozier1, Olga Ousova1, Grard Raffard2, Yannick Crmillieux1

1Cardio-Thoracic Center of Bordeaux, University of Bordeaux Segalen, Bordeaux, France, France; 2Centre de Rsonance Magntique des Systmes Biologiques, University of Bordeaux Segalen, Bordeaux, France, France

Ultra-short echo time (UTE) MRI was already shown to be appropriate for the quantification of the peribronchovascular inflammation typical of the first phase of the chosen ovalbumin model of asthma. The high quality of the images indicated the possibility of extending the protocol until the last phases of the model, in order to assess also the remodeling associated with the disease.