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Abstract #0649

Quantification of Ventilation and Perfusion Using Non-Contrast Enhanced Quasi-Randomly Acquired DC Gated 1H Lung Imaging

Andr Fischer1, Christian O. Ritter1, Stefan Weick2, Dietbert Hahn3, Herbert Kstler1

1Institute of Radiology, University of Wuerzburg, Wuerzburg, Bavaria, Germany; 2Department of Experimental Physics 5, University of Wuerzburg, Wuerzburg, Bavaria, Germany; 3Institute of Radiology, University of Wrzburg, Wuerzburg, Bavaria, Germany

This abstract describes the quantification of pulmonary perfusion and ventilation using non-contrast enhanced quasi-randomly acquired DC gated 1H lung imaging. By properly selecting data according to the DC gating signal which reflects signal variations induced by respiration and pulsatile blood flow, images of the respiratory and cardiac standard cycles are obtained. From these, quantification of perfusion (by a concept called AQUAPICSS) and ventilation (by comparing expiration to inspiration signal levels) is possible. Perfusion rates are in accordance with literature values and additionally performed SEEPAGE experiments. Ventilation rates were derived in normal amplitude respiration and are, therefore, lower than previous literature values obtained in maximum amplitude respiration.