Abstract #0814

Detection of Brown Fat Thermogenesis by Hyperpolarized Xenon Gas MR

Rosa Tamara Branca¹, Le Zhang², Christian White¹, Ting He¹

¹Physics and Astronomy, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States; ²Material Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

In vivo temperature measurement of fatty tissues by proton MR is notoriously challenging. Here we demonstrate in vivo temperature measurement by HP Xenon MR. We also show the possibility to directly measure in real time thermogenesis by brown adipose tissue, a tissue which has recently become the focus of much research attention due to its implication in the development of human obesity and type 2 diabetes.