Eric R. Muir1,
Damon P. Cardenas1, 2, Shiliang Huang3, John
W. Roby1, Timothy O. Duong4
1Research
Imaging Institute, University of Texas Health Science Center, San Antonio,
TX, United States; 2Biomedical Engineering, University of Texas
San Antonio, San Antonio, TX, United States; 3Research Imaging
Institute, University of Texas Health Science Center at San Antonio, San
Antonio, TX, United States; 4Research Imaging Institute, UT Health
Science Center at San Antonio, San Antonio, TX, United States
A better understanding of brain physiology and function under hyperbaric oxygen (HBO) could give insight into the effects of HBO treatment for various neurological diseases. However, oxygen has several effects on MRI signals even at atmospheric pressure, so much higher oxygen concentrations under HBO may potentially confound MRI. The goal of this study is to characterize the effects of HBO on T1, T2, T2*, and Bo/frequency of the rat brain. These parameters changed slightly, but MRI was not dramatically affected, paving the way for functional MRI studies under HBO.
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