Tai-Wei Wu1, Ida Ashoori2, 3, Jessica L. Wisnowski2, Marvin D. Nelson2, Thomas G. Perkins4, Jonathan M. Chia4, Ashok Panigrahy5, Stefan Blml2, 3
1Neonatology, Children's Hospital Los Angeles, Los Angeles, CA, United States; 2Radiology, Children's Hospital Los Angeles, Los Angeles, CA, United States; 3Rudi Schulte Research Institute, Santa Barbara, CA, United States; 4Philips Healthcare, Cleveland, OH, United States; 5Radiology, Children's Hospital of Pittsburgh, Pittsburgh, PA, United States
This study uses non-invasive MR spectroscopy to measure regional brain temperatures during and after hypothermia therapy (HT) in newborns with suspicion for hypoxic ischemic encephalopathy. The goal of the study was to determine whether HT is effective in lowering brain temperature, to explore regional differences, and to determine to what extent esophageal/rectal temperatures correlate with brain temperatures. The long-term goal is to use this information to tailer HT to the needs of individual patients.