Abstract #0964

Investigation of Vascular MRI (ASL and SWI) in Complement to RANO Criteria to Characterize Anti-Angiogenic Therapeutic Response of Glioblastomas

Slim Fellah¹, Olivier Chinot², Nadine Girard¹,³, Maxime Guye⁴, Virginie Callot⁵

¹Centre de Rsonance Magntique Biologique et Mdicale (CRMBM), CNRS / Aix-Marseille Universit, Marseille , France; ²Service de Neurochirurgie, Hpital de la Timone, AP-HM, Marseille, France; ³Service de Neuroradiologie, Hpital de la Timone, AP-HM, Marseille, France; ⁴Centre de Rsonance Magntique Biologique et Mdicale (CRMBM), CNRS / Aix-Marseille Universit, Marseille, France; ⁵Centre de Rsonance Magntique Biologique et Mdicale (CRMBM), Aix-Marseille University, Marseille , France

In this study, we performed longitudinal MR follow-up of GBM treated with anti-angiogenics using a multimodal MR protocol. The investigations particularly involved arterial spin-labeling (ASL) and susceptibility weighted imaging (SWI). Both sequences provide vascular information that may be particularly appropriated to evaluate the anti-angiogenic response, in complement to RANO criteria.