Ge Zhang1, Xianlong Wang1, Shilong Lu1, Zhibo Wen1, Jinyuan Zhou2
1Department of Radiology, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China; 2Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States
We explored the imaging features of malignant, brain metastasis, and different grades of glioma using Amide Proton Transfer MR Imaging at 3 Tesla. Results showed that The average APT signal intensities of the viable tumor cores in each tissue groups were significantly higher than those of peritumoral edema or normal-appearing white matter. Metastases had not significantly different APT signal intensities than those of malignant, low-grade and high-grade glioma. APT imaging provides additional diagnostic information to characterize brain metastases non-invasively.