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Abstract #1172

Disrupted Functional Brain Connectivity in the Salience Network of Post Stroke Depression Patients

Ji-Young Kim1, Seong-Uk Jin2, Jee-Hye Seo2, Jang Woo Park2, Jongsu Baek2, Moon Han2, Kyung-Eun Jang2, Young-Hwan Lee*3, Yongmin Chang4, 5

1Medical Science, Kyungpook National University School of Medicine, Daegu, Korea; 2Medical & Biological Engineering, Kyungpook National University, Daegu, Korea; 3Radiology, Catholic University Medical Center, Daegu, Korea; 4Radiology, Kyungpook National University, Daegu, Korea; 5Molecular Medicine, Kyungpook National University , Daegy, Korea

Poststroke depression (PSD), a common and important neuropsychiatric sequela of stroke, is known to be a multifactorial process. In this study, using resting-state fMRI (rs-fMRI), we investigate possible alteration in functional connectivity (FC) in association with PSD in the salience network (SN), which was most functionally relevant to depression.