Abstract #1249

Multi-Spectral Quantitative Regional MRI Analysis in Patients with Temporal Lobe Epilepsy

Diego Cantor¹, Terry Peters², Ali Khan²

¹Robarts Research - Imaging Labs, Western University, London, ON, Canada; ²Imaging Labs, Robarts Research, London, ON, Canada

Temporal Lobe Epilepsy is characterized by a diverse aetiology which is not always evidenced in MRI. The radiologic assessment consists in the identification of hypo/hyper-intensities in temporal structures as well as the comparison (intensity, volume) of homologous structures in the left and right hemispheres. We propose an synergistic, automated method to systematically identify regional abnormalities. Our method extracts temporal lobe regions for every patient on four different quantitative MR maps; extract regional metrics; then compares each patient against a group of volunteers for every region and every metric. A set of abnormal regions is reported for every patient.