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Abstract #1278

The Correlation of Ventricular Arrhythmias in Hypertrophic Cardiomyopathy and the Late Gadolinium Enhancement on Cardiac Magnetic Resonance

Tao Zhao1, Shihua Zhao1, Minjie Lu2, Xiuyu Chen2, Gang Yin2, Qiong Liu1

1Radiology, Fuwai Hospital,Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, China; 2Radiology, Fuwai Hospital, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing, China


To evaluate the correlation between the ventricular arrhythmias, including frequent premature ventricular arrhythmia (PVC), doublets and non-sustained ventricular tachycardia (NSVT) on 24h Holter electrocardiogram (ECG) in HCM, and the late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR). Patients with LGE had a nearly 6-fold higher risk of NSVT than those LGE negative patients. The correlation coefficient between the fatal ventricular arrhythmia and the LGE score was 0.680. In multivariate analysis, LA anteroposterior diameter and LGE score were the independent determinants of NSVT. Ventricular arrhythmias are closely correlated with the LGE of CMR, and its prevalence is increased with the increase of LGE extent.