Bruce S. Spottiswoode1, Aurelien F. Stalder2, Mehmet Gulsun3, Michael Markl4, 5
1Cardiovascular MR R&D, Siemens Healthcare, Chicago, IL, United States; 2Magnetic Resonance, Imaging & Therapy, Healthcare Sector, Siemens AG, Erlangen, Germany; 3Siemens Corporation, Corporate Technology, Princeton, NJ, United States; 4Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States; 5Department of Biomedical Engineering, Northwestern University Feinberg School of Medicine, Chicago, IL, United States
Pulse wave velocity (PWV) has been shown to be a reliable surrogate marker for cardiovascular disease. In this work, we described a method for automatically estimating PWV from 4D flow data after manually prescribing only the start and end points of the vessel. High temporal resolution 4D and 2D phase contrast flow data of the thoracic aorta were acquired in 9 healthy volunteers. The PWV derived from 4D and 2D flow data were in agreement with each other and with the literature, and sub sampling to a more typical temporal resolution had the effect of reducing the PWV estimates.