Abstract #1465

Helium-3 ADC at Very Short Time Scales Using an SSFP-Based Imaging Pulse Sequence

Karen E. Mooney¹,², John P. Mugler, III³, Talissa A. Altes³, Gordon D. Cates, Jr.²,³, Eduard E. De Lange³, Jaime F. Mata³, William A. Tobias², G. Wilson Miller³

¹Radiation Oncology, University of Maryland SOM, Baltimore, MD, United States; ²Physics, University of Virginia, Charlottesville, VA, United States; ³Radiology, University of Virginia, Charlottesville, VA, United States

In this work, we have measured the Helium-3 diffusion coefficient in human volunteers using a balanced-SSFP pulse sequence. The increase in SNR due to the use of SSFP enabled us to measure the ADC at a diffusion time of only &[Delta]&[ident]500&[mu]s.