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Abstract #1482

19F Gas Flow Measurement of C3F7H During Constant Flow and High Frequency Oscillatory Ventilation

Janet Friedrich1, Daniel Feldmann2, Lars Krenkel2, Claus Wagner2, Laura Maria Schreiber1

1Department of Radiology, Johannes Gutenberg University Medical Center, Mainz, Germany; 2Institute of Aerodynamics and Flow Technology, German Aerospace Center, Gttingen, Germany

The aim of the current study is the development of MRI methods that enable the investigation of gas flow mechanisms during high frequency oscillatory ventilation. This work includes flow measurements during three constant flows (19.9, 30.6 and 41.4 L min-1) and the comparison to direct numerical simulations (DNS) using a second-order-acurate finite-volume method and to data measured with a volume flow meter. 19F-MRI, DNS and flow meter data are in good agreement. Flow measurements during HFOV of 4 Hz were successfully performed and velocity profiles could be recorded at different phases of the ventilation cycle.