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Abstract #1560

The Effect of Iodinated Contrast Media on the Renal GFR as Evaluated by ASL MRI

Jing Wang1, Yudong Zhang2, Jue Zhang1, Xiaoying Wang3, Jing Fang4

1Academy for Advanced Interdisciplinary Studies, Peking Unversity, Beijing, China; 2Department of Radiology, The First Affiliated Hospital With Nanjing Medical University, Nanjing, China, Beijing, China; 3Department of Radiology, Peking University First Hospital, Beijing, China; 4Peking University, Beijing, China

This study developed an approach for renal perfusion and glomerular filtration rate mapping based on the combination of pulsed arterial spin labeling technique and a spin-echo EPI with multiple TEs sequence on clinical 3T MR. Each of ten healthy young subjects accepted 12 breath-hold ASL scans for different TEs acquisition. Based on the proposed method, the RBF, blood R2* and GFR maps were obtained simultaneously. We hope that this MR technique can be combined with other functional methods to provide a complete noninvasive assessment of renal status in a single examination.