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Abstract #1598

Quadrant Analysis of Femoral Head Perfusion After Fracture Using Dynamic Contrast Enhanced MRI

Jonathan P. Dyke1, Lionel E. Lazaro2, Carolyn Hettrich3, Craig Klinger4, Keith Hentel1, Dean Lorich2, 4

1Radiology, Weill Cornell Medical College, NY, United States; 2Orthopaedic Surgery, Weill Cornell Medical College, New York, NY, United States; 3Orthopaedic Surgery, University of Iowa, Iowa City, IA, United States; 4Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, United States

Quantitative dynamic contrast enhanced (DCE-MRI) was performed on subjects (n=29) presenting with fractures of the femoral neck. A 2 compartment model was used to assess perfusion in the entire femoral head as well as each quadrant on injured and control sides. Model parameters showed increased perfusion on the control vs. fracture side in all areas except the rate of elimination (kel). Quadrant analysis confirmed decreased (kel) in the fractured side hypothesized to be caused by venous obstruction and intra-articular pressure. This technique may be used to assess femoral head perfusion and lead to identifying regions at risk for avascular necrosis.