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Abstract #1736

Noncompressive MR Elastography of Breasts

Jun Chen1, Kathleen Brandt1, Karthik Ghosh1, Roger C. Grimm1, Kevin J. Glaser1, Jennifer Kugel1, Richard L. Ehman1

1Mayo Clinic, Rochester, MN, United States

Early and accurate diagnosis of breast cancer is critical for optimal treatment. There is considerable interest in exploring the potential of MR elastography to enhance the specificity of contrast-enhanced MRI for characterizing breast lesions. However, as previously implemented MR-elastography has used mechanical drivers that require contact and compression of the breasts, which can change breast tissue stiffness. This study rizes the development of a new noncompressive MR Elastography technique that does not require any contact with or compression of the breasts and reports the results from a preliminary study of 7 healthy volunteers and one patient with invasive ductal carcinoma.