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Abstract #1789

Uniform and Broadband 31P MRSI Combined with 1H MRSI in the Human Prostate Using a Double Tuned Quadrature Endorectal Coil

Mariska P. Luttje1, Michel Italiaander1, Catalina S. Arteaga de Castro1, Wybe J.M. van der Kemp1, Marco van Vulpen1, Peter R. Luijten1, Uulke A. van der Heide2, Dennis W.J. Klomp1

1Imaging Division, Univerity Medical Center, Utrecht, Netherlands; 2Department of Radiotherapy, the Netherlands Cancer Instituut - Antoni van Leeuwenhoek hospital , Amsterdam, Netherlands

In this study at 7T, we implemented a double tuned ERC as a quadrature 1H transceiver and 31P transceiver. As the T1 values of the detectable phospholipids are similar, a progressive saturated pulse acquire sequence (i.e. short TR and optimized flip angle) was used to ensure a uniform and broadband detection of the phospholipid metabolites. Validated by phantom experiments, the detection of both 1H and 31P MR spectra in a patient with prostate cancer using the 1H/31P ERC has been demonstrated