Uniform and Broadband 31P MRSI Combined with 1H MRSI in the Human Prostate Using a Double Tuned Quadrature Endorectal Coil

Mariska P. Luttje¹, Michel Italiaander¹, Catalina S. Arteaga de Castro¹, Wybe J.M. van der Kemp¹, Marco van Vulpen¹, Peter R. Luijten¹, Uulke A. van der Heide², Dennis W.J. Klomp¹

In this study at 7T, we implemented a double tuned ERC as a quadrature ¹H transceiver and ³¹P transceiver. As the T1 values of the detectable phospholipids are similar, a progressive saturated pulse acquire sequence (i.e. short TR and optimized flip angle) was used to ensure a uniform and broadband detection of the phospholipid metabolites. Validated by phantom experiments, the detection of both ¹H and ³¹P MR spectra in a patient with prostate cancer using the ¹H/³¹P ERC has been demonstrated