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Abstract #1831

MR-Based Targeting of Histotripsy Therapy at 7T

Steven P. Allen1, Timothy L. Hall1, Charles A. Cain1, Luis Hernandez-Garcia1

1Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Here we investigate the feasibility of using HIFU induced cavitational bubble clouds as a targeting and steering mechanism for MR-guided cavitation-based ultrasound therapy. GRE imaging sequences are sensitive to the presence of the transient bubble cloud. Further, the transient cloud's associated B0 field perturbation behaves much like that of a stationary bubble.