MR-Based Targeting of Histotripsy Therapy at 7T

Steven P. Allen¹, Timothy L. Hall¹, Charles A. Cain¹, Luis Hernandez-Garcia¹

Here we investigate the feasibility of using HIFU induced cavitational bubble clouds as a targeting and steering mechanism for MR-guided cavitation-based ultrasound therapy. GRE imaging sequences are sensitive to the presence of the transient bubble cloud. Further, the transient cloud's associated B0 field perturbation behaves much like that of a stationary bubble.