Roel Deckers1, Baudouin Denis de Senneville1, 2, Mario Ries1, Hanne D. Heerkens3, Cornelis A.T. van den Berg3, Marco van Vulpen3, Chrit T.W. Moonen1
1Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands; 2CNRS/Universit Bordeaux 1/INRIA, Institut de Mathmatiques de Bordeaux UMR 5251, Talence, Gironde, France; 3Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands
MRI guided High Intensity Focused Ultrasound (HIFU) might become a new tool for the non-invasive image-guided treatment of pancreatic cancer. For ablation as well as hyperthermia treatments accurate MR temperature measurements are essential. In this study the accuracy of PRFS based thermometry in the pancreas was investigated in volunteers. Temperature standard deviation of 2-3 degrees was obtained in the pancreas during breath hold and during free breathing (after correction for motion related errors using a multi-baseline approach). We conclude that temperature mapping for guiding a HIFU ablation procedure is feasible in the pancreas.