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Abstract #1994

Evaluation of Lactate Detection Using Selective Multiple Quantum Coherence in Phantoms and Brain Tumours

Lisa Maria Harris1, Nina Tunariu2, Toni Wallace, Nandita M. deSouza, Martin O. Leach, Geoffrey Payne

1Institute of Cancer Research and Royal Marsden Hospital , Sutton, Surrey, United Kingdom; 2Institute of Cancer Research and Royal Marsden Hospital, Institute of Cancer Research and Royal Marsden Hospital, Sutton, Surrey, United Kingdom


A study using a selective homonuclear multiple quantum coherence transfer transfer (SelMQC) sequence to accurately quantify lactate by suppressing lipid signals is presented. Phantom studies are shown to verify both the lipid suppression and the lactate detection and the performance of the sequence was assessed in brain tumours where the presence of lactate and lipids are both expected.

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