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Abstract #2025

Gradient Induced Sideband Artifacts in Non Water-Suppressed Proton CSI of the Human Brain at 9.4 T

Grzegorz L. Chadzynski1, 2, Rolf Pohmann2, Gunamony Shajan2, Rupert Kolb3, Uwe Klose3, Klaus Scheffler1, 2

1Dept. Biomedical Magnetic Resonance, University Hospital Tuebingen, Tuebingen, Germany; 2Dept. High-Field Magnetic Resonance, Max Planc Institute for Biological Cybernetics, Tuebingen, Germany; 3Dept. Neuroradiology, University Hospital Tuebingen, Tuebingen, Germany

CSI without water suppression offers several advantages, like the possibility to use the water signal for absolute quantification. However, the unsuppressed spectra are hampered by gradient induced sidebands, which have to be removed before the quantification. Despite known difficulties (shorter T2 relaxation time, larger B0 and B1 inhomogeneities), previous studies demonstrated that CSI at ultra-high magnetic field is feasible. The aim of this study was to verify the feasibility of short TE proton CSI on the human brain without water suppression at the field strength of 9.4 T and to examine the influence of sidebands on the measured spectra.