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Abstract #2189

Renal Perfusion Imaging with Two-Dimensional Navigator Gated Arterial Spin Labeling

Huan Tan1, Ioannis Koktzoglou2, 3, Pottumarthi Vara Prasad2, 3

1NorthShore University HealthSystem, Evanston , IL, United States; 2NorthShore University HealthSystem, Evanston, IL, United States; 3The University of Chicago Pritzker School of Medicine, Chicago, IL, United States

A single breath-hold scan does not provide enough time for signal averaging needed by arterial spin labeling technique in renal perfusion measurement. In our study, we have implemented a novel two-dimensional (2D) navigator technique in concert with FAIR True-FISP to minimize respiratory motion via retrospective reconstruction and allow for multiple averages during free-breathing acquisition. The 2D navigator-gated approach achieved good image quality in patients while the breath-hold results were unusable. Given the limitation of using contrast agents in patients with compromised renal function, free breathing ASL offers a non-invasive method to evaluate renal perfusion.