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Abstract #2253

Network Diffusion Models for Functional Brain Connectivity Networks

Farras Abdelnour1, Henning Voss1, Ashish Raj1

1Radiology, Weill Cornell Medical College, New York, NY, United States

We present a simple and intuitive network diffusion model which produces an accurate mathematical description of the structure-function relationship. We hypothesize that resting state functional relationships between brain regions result from this diffusion process applied to the structural network during rest. The network diffusion model applied to the structural networks closely predicts both the spatial and temporal correlation structures seen in the functional networks. We compare our work with published models. The proposed model is simple yet offers improved estimates of functional connectivity.