Spontaneous fMRI-BOLD Power Spatial Distribution: Comparison Between Awake State and Under Isoflurane Anesthesia in the Rat

Wen-Ju Pan¹, Matthew E. Magnuson¹, Garth Thompson¹, Shella Keilholz¹

As a first step toward understanding the difference of brain baseline activity in resting state fMRI between awake and isoflurane-anesthetized states in the rat model, we examined the BOLD spectral powers across brain distributions between the two states, and demonstrated the potential usefulness of mapping low frequency BOLD power to assess brain regional activity.