Mikio Suga1, 2, Takayuki Obata2, Hajime Ikeda1, Atsuhisa Koyama1, Tetsuya Wakayama3, Riwa Kishimoto2
1Graduate School of Engineering, Chiba University, Chiba, Japan; 2National Institute of Radiological Sciences, Chiba, Japan; 3GE Healthcare Japan, Hino, Tokyo, Japan
Magnetic resonance elastography (MRE) is a noninvasive technique for measuring tissue viscoelasticity. Switching-gradient(s)-induced vibration (SGIV) can be used as a mechanical driving mechanism for MRE. The advantage of this approach is that it can be easily adapted for clinical application, but the reproducibility of measurements has not been confirmed. To evaluate reproducibility of MRE scanning with SGIV (MREwSGIV), this study compared shear wave amplitudes in gel phantoms of different weight and measured the viscoelasticity of the human brain at specific mechanical resonance frequencies twice. The results suggest that MREwSGIV enables reproducible measurements of brain elasticity.