Meeting Banner
Abstract #2493

Relevance of Morphological Binary Information for L2 and L1 Total Variation Methods in Quantitative Susceptibility Mapping and Reconstruction Quality Assessment Without Presence of the Ground Truth

Diana Khabipova1, Yves Wiaux2, 3, Rolf Gruetter4, 5, Jos P. Marques1, 5

1LIFMET, EPFL, Lausanne, Switzerland; 2Electrical Engineering, EPFL, Lausanne, Switzerland; 3Radiology, UniGe, Geneva, Switzerland; 4LIFMET, cole Polytechnique Fdrale de Lausanne, Lausanne, Switzerland; 5Radiology, UNIL, Lausanne, Switzerland

Phase imaging has been demonstrated to achieve a good contrast between and within brain tissues at 7T. However, phase imaging suffers from a non-local contrast variation which can be overcome by calculating the underlying magnetic susceptibility maps. As this problem is ill-posed, many regularization methods have been proposed over the past years. In this abstract we do a thorough comparison of some of these methods, focus on the impact of the prior information on the reconstructed susceptibility maps and propose a method to evaluate the quality of the susceptibility reconstruction in the absence of a ground truth.