Meeting Banner
Abstract #2883

Comparing Differences in Alzheimer's Disease Classification Between Structural and Resting-State Functional MRI Biomarkers

Guangyu Chen1, Chunming Xie1, Guangyu Chen1, Wenjun Li1, B. Douglas Ward1, Jennifer L. Jones2, Malgorzata Franczak2, Piero G. Antuono2, Shi-Jiang Li1

1Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 2Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, United States

Data from 65 Alzheimer's disease and 136 cognitively normal subjects were included in the study. We compared Alzheimer's disease classification techniques, using structural and resting-state functional MRI biomarkers. When the RfMRI classification result agreed with the structural MRI classification result, the subjects were classified with 90% accuracy. The incongruous classification results may predict disease conversion or treatment response.