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Abstract #2889

Iron-Related Microstructural Alterations in Deep Gray Matter: Correlations from Diffusional Kurtosis Imaging and Quantitative Susceptibility Mapping

Nan-Jie Gong1, Chun-Sing Wong1, Chun-Chung Chan2, Lam-Ming Leung2, Queenie Chan3

1Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China; 2United Christian Hospital, Hong Kong, China; 3Philips Healthcare, Hong Kong, China

Using both quantitative susceptibility mapping (QSM) and diffusional kurtosis imaging (DKI) methods, we investigated age-related iron depositions in subcortical gray matters of globus pallidus (GP) and putamen (Pu). Besides, the contribution of iron deposition with aging to microstructural alterations in deep gray matter has also been studied by testing correlations between DKI parameters and susceptibility.