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Abstract #2888

Impact of Short-Term Administration of Oral Minocycline, a Repurposed Anti-Neuroinflammatory Agent, on MR and Neuropsychological Biomarkers of MCI and AD

Thao T. Tran1, Cherise Charleswell1, Nick O'Dell1, June Liu1, Michael Miller2, Michael Lindsey3, Brian D. Ross1

1Clinical MR, HMRI, Pasadena, CA, United States; 2Webster's Community Pharmacy, Altadena, CA, United States; 3Huntington Memorial Hospital, Pasadena, CA, United States

We demonstrate the impact of minocycline on mild cognitive impairment (MCI) and Alzheimer's disease (AD) by employing quantified MR neuro-imaging (qMRI) and neurospectroscopy (MRS).