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Abstract #2986

Studying Brain Motor, Language and Auditory Functions and Associated Functional Connectivity on AVM Patients by fMRI and Resting State fMRI

Bob L. Hou1, Majid Haghighat Ahoar1, Sanjay Bhatia2, Rachel Lagos1, Jeff S. Carpenter1

1Radiology, WVU, Morgantown, WV, United States; 2Surgery, WVU, Morgantown, WV, United States

Arteriovenous malformations (AVM) lesion cause venous hypertension within the draining vein and relative arterial hypotension in the surrounding brain tissue. This steal effect in which high blood volume and low pressure in the feeding arteries create hypoperfusion in surrounding normal brain has been reported to lead to brain functional reorganization. In this study, we investigated brain motor, language and auditory functions and associated functional connectivity for AVM patients by fMRI and resting state fMRI (rfMRI). We hypnotized that this condition results in changes (i.e., reorganization) in brain functions and or in brain functional connectivity