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Abstract #3065

Alternative Sequence for Arterial Input Function Measurements for Bolus Tracking Perfusion Imaging in the Brain

Elias Kellner1, Irina Mader2, Marco Reisert1, Valerij G. Kiselev1

1Department of Radiology, University Hospital Freiburg, Freiburg, Germany; 2Section of Neuroradiology, University Hospital Freiburg, Freiburg, Germany

We recently presented a method for a quantitative determination of the arterial input function in the carotid arteries. The AIF-measurement plug-in in the standard DSC perfusion sequence used the apparent shift in the arterial position in one-dimensional projection images and was optimised for high doses of contrast. Here we demonstrate an alternative AIF measurement plug-in for low-dose clinical measurements based on fast two-dimensional readout and the phase AIF. Efficient background suppression using inversion recovery remains a crucial component of the method. We present a comparative discussion of both methods in relation to the dose, tracer type, and the field strength.