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Abstract #3150

Knowledge-Based Tractography Using Path Finding by Dynamic Programing

Muwei Li1, J. Tilak Ratnanather2, Yajing Zhang1, Hangyi Jiang1, Kenichi Oishi1, Michael I. Miller2, Susumu Mori1

1The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States; 2Center for Imaging Science, Johns Hopkins University, Baltimore, MD, United States

A knowledge-guided path-finding approach is proposed in this study. Combined with the automated brain segmentation, this approach can automatically generate 106 tracts based on our anatomical knowledge.This tool can be used to investigate tract-specific white matter anatomical states in various brain disorders.