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Abstract #3337

Simultaneous Quantification of Cerebral Arterial Blood Volume and Flow During Visual Stimulation in Humans at 3 T.

Tae Kim1, Seong-Gi Kim1, Kyongtae Ty Bae1

1University of Pittsburgh, Pittsburgh, PA, United States

Cerebral blood flow (CBF) and arterial blood volume (CBVa) in baseline and their changes associated with visual stimulation in humans were successfully measured using multi-slice FAIR with bipolar gradients at 3T. CBF and CBVa values were dynamically synchronous and highly overlapping during visual stimulation, suggesting that the dilation of CBVa is the major contributor to an increase in CBF in normal physiology. Simultaneous quantification of CBV and CBVa without the use of exogenous contrast agents is highly useful and clinical significant for the assessment of cerebrovascular viability and pathological conditions.