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Abstract #3357

Echo Time Dependence of Resting Signal Fluctuations in USPIO Based Cerebral Blood Volume Imaging: Implications for Task-Based and Resting State fMRI

Deqiang Qiu1, Greg Zaharchuk1, Thomas Christen1, Wendy W. Ni1, Michael E. Moseley1

1Radiology, Stanford University, Stanford, CA, United States

In this study, we characterize the noise behaviour of post contrast fMRI (termed ICE-BVI) using the ultrasmall superparamagnetic iron particle (USPIO) under different echo times and static SNR. The result is useful in guiding study designs in task based and resting state ICE-BVI. It suggests that higher resolution task based ICE-BVI can be achieved without significantly sacrificing sensitivity, and that effective methods for reducing physiological noises are important for resting state ICE-BVI for studying functional connectivity.