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Abstract #3367

Agreement Between Quantitative and Radiologist-Assessed Qualitative Background Parenchymal Breast Enhancement at MRI

Ania Azziz1, Ella Jones2, Catherine Klifa2, David C. Newitt2, Elissa Price2, Nola M. Hylton3, Bonnie N. Joe2

1Radiology , UCSF, San Francisco, CA, United States; 2Radiology, UCSF, San Francisco, CA, United States; 3Radiology, University of California San Francisco, San Francisco, CA, United States

Breast MRI background parenchymal enhancement (BPE) can interfere with MRI interpretation and is associated with breast cancer risk. The purpose of this study is to define whole breast BPE using an accurate quantitative method in a normal population and compare this quantitative measure to radiologist-assessed qualitative enhancement in order to facilitate understanding of BPE. Quantitative BPE in the normal population does not exceed 57%. Additionally, quantitative and qualitative BPE are significantly correlated, however, qualitative BPE trends towards higher values. These findings serve as benchmark data for accurate quantitative values of MR BPE in normal patients.