Abstract #3366

Comparative Measurement of Breast Volume and Dense Tissue Volume Based on Breast MRI and Low Dose Chest CT

Xiaoyong Wang¹, Jeon-Hor Chen², Yen-Hsiu Liao³, Peter T. Fwu¹, Muqing Lin¹, Min-Ying Su¹

¹Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California, Irvine, CA, United States; ²Center for Functional Onco-Imaging, Department of Radiological Sciences, University of California Irvine, Irvine, CA, United States; ³Department of Radiology, China Medical University Hospital, Taichung, Taiwan

We reported a breast density segmentation method for low dose chest CT, which is widely used for lung cancer screening. The method was based on algorithms used for MRI segmentation (FCM clustering and region growing & fitting). Fifteen healthy subjects who received both CT for lung cancer screening and MRI for breast cancer screening were analyzed. The breast volume, fibroglandular tissue volume, and percent density measured on CT and MRI were highly correlated, with r > 0.98. The results show that it is feasible to segment breast density based on chest CT to yield consistent measurements compared to MRI.