Pascal Baltzer1, Wolfgang Bogner2, Hubert Bickel1, Olgica Zaric2, Thomas Helbich3, Georg Wengert1, Katja Pinker-Domenig1
1Dept. of Radiology, Divison of Molecular and Gender Imaging, Medical University Vienna, Vienna, Austria; 2MR Centre of Excellence, Medical University Vienna, Vienna, Austria; 3Dept. of Radiology, Divison of Molecular and Gender Imaging, Medical University of Vienna, Vienna, Austria
To solely apply DWI to a non-selected group of MRI patients and to compare its diagnostic accuracy to ceMRI in a multi-reader study. 60 consecutive patients with an imaging abnormality were included in this retrospective IRB approved study. Two experienced readers trained in different institutions independently read DWI and CE-MRI examinations and assigned a diagnosis (BIRADS scale 1=no lesion to 5= definite malignancy). Sensitivity, specificity, diagnostic accuracy and inter-reader variability (kappa statistics) were calculated for both readers. DWI for breast cancer diagnosis in breast MRI is feasible with a comparable sensitivity equal to ceMRI.