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Abstract #3570

Amplitude Spectrum of Spontaneous Fluctuations in Idiopathic Generalized Epilepsy

Zhengge Wang1, 2, Zhiqiang Zhang2, Qiang Xu2, Guangming Lu2

1Dept. of Radiology, Nanjing Drum Tower Hospital, Nanjing, Jiangsu, China; 2Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu, China


The amplitude information of low-frequency oscillations was found meaningful in investigating the regional spontaneous neuronal activity. The amplitude of spectral component in different frequency bands exhibited distinct spatial features. We used fractional amplitude of low-frequency fluctuation (fALFF) to investigate the oscillation abnormality in idiopathic generalized epilepsy, and further extended the analysis to the fALFF across different frequency bands.