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Abstract #3677

Susceptibility Weighted Imaging of Iron-Labeled C6-Glioma in Rats at 7T

Monika Huhndorf1, Olga Will2, Rolf Mentlein3, Olav Jansen1, Susann Boretius2

1Institute of Neuroradiology, University Medical Center Schleswig-Holstein, Kiel, Germany; 2Biomedical Imaging, Diagnostic Radiology, Christian-Albrechts-University, Kiel, Germany; 3Institute of Anatomy, Christian-Albrechts-University, Kiel, Germany

High resolution susceptibility weighted imaging (SWI) was used in comparison with other MR-contrasts at 7T in order to visualize iron-labeled C6-glioma cells in a rat model. Although even very low iron concentrations were detectable by SWI, no significant iron accumulation was found at the margin of advanced tumors, suggesting persistence of the iron particles at the site of the primary cells in the tumor center.