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Abstract #3888

Biopolymer Coated Gd2O3 Nanoparticles for MRI Contrast Agent

Md. Wasi Ahmad1, Kattel Krishna1, Badrul Alam Bony1, Wenlong Xu1, Tirusew Tegafaw1, Woo Choul Heo1, Yongmin Chang2, Gang Ho Lee1

1Chemistry, Kyungpook National University, Daegu, Korea; 2Molecular Medicine School of Medicine, Kyungpook National University, Daegu, Korea

The surface modified Gd2O3 nanoparticles as an active ingredient has a higher relaxation rate compared to currently commercialized MRI contrast agent. The performance of nanoparticles for biomedical applications is highly dependent on the nature and quality of surface coating materials. In particular, the development of functionalized nanoparticles for magnetic resonance imaging (MRI) requires the grafting of hydrophilic and biocompatible polymers, this polymer enhances the steric repulsion and therefore the stability of the colloids