Abstract #3888

Biopolymer Coated Gd2O3 Nanoparticles for MRI Contrast Agent

Md. Wasi Ahmad¹, Kattel Krishna¹, Badrul Alam Bony¹, Wenlong Xu¹, Tirusew Tegafaw¹, Woo Choul Heo¹, Yongmin Chang², Gang Ho Lee¹

¹Chemistry, Kyungpook National University, Daegu, Korea; ²Molecular Medicine School of Medicine, Kyungpook National University, Daegu, Korea

The surface modified Gd₂O₃ nanoparticles as an active ingredient has a higher relaxation rate compared to currently commercialized MRI contrast agent. The performance of nanoparticles for biomedical applications is highly dependent on the nature and quality of surface coating materials. In particular, the development of functionalized nanoparticles for magnetic resonance imaging (MRI) requires the grafting of hydrophilic and biocompatible polymers, this polymer enhances the steric repulsion and therefore the stability of the colloids