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Abstract #3934

Cerebral Perfusion Imaging with Hyperpolarized 13C-Tert-Butanol at 9.4 Tesla: Long Relaxation at High Fields

Leo L. Tsai1, Xiaoen Wang1, Gopal Varma1, David C. Alsop1, Aaron K. Grant1

1Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States

Hyperpolarized 13C-tert-butanol is a freely diffusible agent which allows for high SNR cerebral perfusion imaging. At 9.4 Tesla, we demonstrate relatively long in-vivo cerebral relaxation times (T2 = 0.71 0.03 s and T1 = 78 26 s), demonstrating feasibility for high-field imaging and spectroscopy with this agent.