Abstract #3934

Cerebral Perfusion Imaging with Hyperpolarized 13C-Tert-Butanol at 9.4 Tesla: Long Relaxation at High Fields

Leo L. Tsai¹, Xiaoen Wang¹, Gopal Varma¹, David C. Alsop¹, Aaron K. Grant¹

¹Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States

Hyperpolarized ¹³C-tert-butanol is a freely diffusible agent which allows for high SNR cerebral perfusion imaging. At 9.4 Tesla, we demonstrate relatively long in-vivo cerebral relaxation times (T2 = 0.71 0.03 s and T1 = 78 26 s), demonstrating feasibility for high-field imaging and spectroscopy with this agent.