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Abstract #3982

Multi-Center Reproducibility of Short Echo Time Single Voxel 1H MRS of the Human Brain at 7T with Adiabatic Slice-Selective Refocusing Pulses

B.L. van de Bank1, Uzay E. Emir2, Vincent Oltman Boer3, Jack JA van Asten1, Jannie P. Wijnen3, 4, H.E. Kan4, G. z2, Dennis W. J. Klomp3, Tom W.J. Scheenen1, 5

1Radiology, Radboud Nijmegen Nijmegen Medical Center, Nijmegen, Netherlands; 2Center for Magnetic Resonance Research, Minneapolis, MN, United States; 3Radiology, University Medical Center Utrecht, Utrecht, Netherlands; 4Radiology, Leiden University Medical Center, Leiden, Netherlands; 5Erwin L. Hahn Institute, Essen, Germany

The reproducibility and robustness of the semi-LASER sequence was investigated at 7T. Seven volunteers were scanned twice each at 4 different 7T systems (2 Siemens & 2 Philips). Excellent quality spectra were obtained from gray and white matter at all sites. The within-subject variations and hence within-institution variations were low, meaning that the technique is robust and reproducible. Few between-institution variations were found.